研究成果

Original Paper 2019

Yamagaki, T., Yamazaki, T. “Troubleshooting carry-over in LC-MS analysis of biomolecules; The case of neuropeptide Y.” Mass Spectrom., S0083 (2019). [Publisher] (open access)

Sugahara, K., Kitao, K., Watanabe, T., Yamagaki, T. “Imaging mass spectrometry analysis of flavonoids in blue viola petals and their enclosure effects on violanin during color expression.” Analytical Chemistry. 91, 896-902 (2019). [Publisher] (open access)

Nomura, K., Yamaguchi, T., Mori, S., Fujikawa, K., Nishiyama, K., Shimanouchi, T., Tanimoto, Y., Morigaki, K., Shimamoto, K. “Alteration of membrane physicochemical properties by two factors for membrane protein integration” Biophys. J., 117, 99–110. (2019) [Publisher] (open access)

Tera, M., Luedtke, N. W. “Three-Component Bioorthogonal Reactions on Cellular DNA and RNA” Bioconjug. Chem., 30, 2991–2997. (2019) [Publisher]

Yamamoto, T., Yamagaki, T., Satake, H. “Development of software for deep analysis of protein dynamics as determined by MALDI mass spectrometry-based hydrogen/deuterium exchange.” Mass Spectrom., S0082 (2019). [Publisher] (open access)

Sawasato, K., Sato, R., Nishikawa, H., Iimura, N., Kamemoto, Y., Fujikawa, K.,Yamaguchi, T., Kuruma, Y., Tamura, Y., Endo, T., Ueda, T., Shimamoto, K., Nishiyama, K. “CdsA is involved in biosynthesis of glycolipid MPIase essential for membrane protein integration in vivo” Sci. Rep., 9, 1372 (2019) [Publisher] (open access)

Hoshino, A., Mizuno, T., Shimizu, K., Mori, S., Fukada-Tanaka, S., Furukawa, K., Ishiguro, K., Tanaka, Y., Iida, S. “Generation of yellow flowers of the Japanese morning glory by engineering its flavonoid biosynthetic pathway toward aurones.” Plant Cell Physiol. 60, 1871–1879 (2019). [Publisher] (open access)

Ishikawa, Y., Murai, Y., Sakata, M., Mori, S., Matsuo, S., Senuma, W., Ohnishi, K., Hikichi, Y., Kai, K. “Activation of ralfuranone/ralstonin production by plant sugars functions in the virulence of Ralstonia solanacearum.” ACS Chem. Biol. 14, 1546–1555 (2019). [Publisher]

Murakami, Y., Iwabuchi, H., Ohba, Y., Fukami, H. “Analysis of volatile compounds from Chili peppers and characterization of Habanero (Capsicum chinense) volatiles.” J. Oleo Sci. 68, 1251–1260 (2019). [PubMed] (open access)

Nomura, Y., Seki, H., Suzuki, T., Ohyama, K., Mizutani, M., Kaku, T., Tamura, K., Ono, E., Horikawa, M., Sudo, H., Hayashi, H., Saito, K., Muranaka, T. “Functional specialization of UDP-glycosyltransferase 73P12 in licorice to produce a sweet triterpenoid saponin, glycyrrhizin.” Plant J. 99, 1127-1143 (2019). [Publisher] (open access)

Ono E*, Waki T*, Oikawa D, Murata J, Shiraishi A, Toyonaga H, Kato M, Ogata N, Takahashi S,Yamaguchi MA, Horikawa M, Nakayama T. (2019) “Glycoside-specific glycosyltransferases catalyze regio-selective sequential glucosylations for a sesame lignan, sesaminol triglucoside.” Plant J. 101(5), 1221-1233. [PubMed] (*, equal contributors.) open access

Yamashiro T*, Shiraishi A*, Satake H, Nakayama K. (2019) “Draft genome of Tanacetum cinerariifolium, the natural source of mosquito coil.” Sci Rep. 9(1), 18249. [PubMed] (*, equal contributors.) open access

Matsubara S, Shiraishi A, Osugi T, Kawada T, Satake H. (2019) “The regulation of oocyte maturation and ovulation in the closest sister group of vertebrates.” eLife. 8, pii: e49062. [PubMed] open access

Aoyama M*, Shiraishi A*, Matsubara S, Horie K, Osugi T, Kawada T, Yasuda K, Satake H.(2019) “Identification of a New Theca/Interstitial Cell-Specific Gene and Its Biological Role in Growth of Mouse Ovarian Follicles at the Gonadotropin-Independent Stage.” Front Endocrinol (Lausanne). 10, 553. [PubMed] (*, equal contributors.) open access

Tera M*, Koyama T*, Murata J, Furukawa A, Mori S, Azuma T, Watanabe T, Hori K, Okazawa A,Kabe Y,Suematsu M, Satake H, Ono E, Horikawa M.(2019) “Identification of a binding protein for sesamin and characterization of its roles in plant growth.” Sci. Rep. 9(1), 8631. [PubMed] (*, equal contributors.) open access

Nagasawa K, Matsubara S, Satake H, Osada M. (2019) “Functional characterization of an invertebrate gonadotropin-releasing hormone receptor in the Yesso scallop Mizuhopecten yessoensis.” Gen. Comp. Endocrinol. 282, 113201. [PubMed]

Shiraishi A, Okuda T, Miyasaka N, Osugi T, Okuno Y, Inoue J, Satake H. (2019) “Repertoires of G protein-coupled receptors for Ciona-specific neuropeptides.” Proc. Natl. Acad. Sci. U S A. 116(16), 7847-7856. [PubMed] open access

Original Paper 2020

Yamagaki, T., Yamazaki, T. “Practical Protocol for Making Calibration Curves for Direct and Sensitive Quantitative LC Orbitrap-MS of Large Neuropeptides.” Mass Spectrom., A0087 (2020). [Publisher] (open access)

Kabe, Y., Takemoto, D., Kanai, A., Hirai, M., Ono, Y., Akazawa, S., Horikawa, M., Kitagawa, Y., Handa, H., Rogi, T., Shibata, H., Suematsu, M. “Annexin A1 Accounts for an Anti-Inflammatory Binding Target of Sesamin Metabolites” NPJ Sci Food 4, 4 (2020). [Publisher] (open access)

Ono, E., Waki, T., Oikawa, D., Murata, J., Shiraishi, A., Toyonaga, H., Kato, M., Ogata, N., Takahashi, S., Yamaguchi, M. A., Horikawa, M., Nakayama, T. “Glycoside-specific glycosyltransferases catalyze regio-selective sequential glucosylations for a sesame lignan, sesaminol triglucoside” Plant J. 101, 1221-1233 (2020). [Publisher] (open access)

Matsubara S, Shiraishi A, Osugi T, Kawada T, Satake H. (2020) “Fractionation of Ovarian Follicles and in vitro Oocyte Maturation and Ovulation Assay of Ciona intestinalis Type A” Bio Protoc. 10(7), doi: 10.21769/BioProtoc.3577 [PubMed] open access

Osugi T, Sasakura Y, Satake H. (2020) “The ventral peptidergic system of the adult ascidian Ciona robusta (Ciona intestinalis Type A) Insights from a transgenic animal model” Sci Rep. 10(1), 1892, doi: 10.1038/s41598-020-58884-w [PubMed] open access.

Matsuo R, Kobayashi S, Furuta A, Osugi T, Takahashi T, Satake H, Matsuo Y. (2020) “Distribution and physiological effect of enterin neuropeptides in the olfactory centers of the terrestrial slug Limax” J Comp Physiol A 206(3), 401-418, doi: 10.1007/s00359-020-01400-2 [PubMed]

Mita M, Osugi T, Takahashi T, Watanabe T, Satake H. (2020) “Mechanism of gamete shedding in starfish: Involvement of acetylcholine in extracellular Ca²⁺-dependent contraction of gonadal walls” Gen Comp Endocrinol. 290, 113401, doi: 10.1016/j.ygcen.2020.113401. [PubMed]

Sugahara K*, Kitao K, Yamagaki T, Koyama T*. (2020) “Practical optimization of LC-MS conditions and pretreatment methods toward the sensitive quantification of auxin in plants”. Rapid Commun. Mass Spectrom. 34, e8625. [PubMed] (*, equal contributors.) open access

Morishita F, Takahashi T, Watanabe T, Uto T, Ukena K, Furumitsu M, Horiguchi T. (2020) “Identification of neuropeptides in gastropod mollusks. – Classical and brand-new approaches” – IOP Conf. Ser.: Earth and Environ. Sci. 456, 012001, doi: 10.1088/1755-1315/456/1/012001 open access

Tsugawa H, Kabe Y, Kanai A, Sugiura Y, Hida S, Taniguchi S, Takahashi T, Matsui H, Yasukawa Z, Itou H, Takubo K, Suzuki H, Honda K, Handa H, Suematsu M. (2020) Short-chain fatty acids bind to apoptosis-associated speck-like protein to activate inflammasomal complex to prevent Salmonella infection. PLoS Biol. 18(9), e3000813. [PubMed] open access

Takahashi T, Shiraishi A, Osawa M. Upregulated nicotinic ACh receptor signaling contributes to intestinal stem cell function through activation of Hippo and Notch signaling pathways. Int Immunopharmacol. 88, 106984. [PubMed]

Mita M, Matsubara S, Osugi T, Shiraishi A, Wada A, Satake H. (2020) “A novel G protein-coupled receptor for starfish gonadotropic hormone, relaxin-like gonad-stimulating peptide” PLoS One. 15(11), e0242877. doi: 10.1371/journal.pone.0242877. [PubMed]. open access.

Mayama S, Hamazaki N, Maruyama Y, Matsubara S, Kimura AP. (2020) “Transcriptional activation of the mouse Scd2 gene by interdependent enhancers and long noncoding RNAs in ovarian granulosa cells” J Reprod Dev. 66, 435-444. doi: 10.1262/jrd.2019-161. [PubMed] open access

Harada E*., Murata J*., Ono E*., Toyonaga H., Shiraishi A., Hideshima K., Yamamoto MP., Horikawa M. (+)-Sesamin-oxidizing CYP92B14 shapes specialized lignan metabolism in sesame. Plant J. 104, 1117-1128 (2020). (*, equal contributors), doi: 10.1111/tpj.14989 [PubMed] open access

Kikuchi A., Takayama H., Tsugane H., Shiba K., Chikamoto K., Yamamoto T., Matsugo S., Ishii K., Misu H., Takamura T. Plasma half-life and tissue distribution of leukocyte cell-derived chemotaxin 2
in mice. Sci Rep 10 (1), 1-11 (2020). [PubMed] open access

Original Paper 2021

Yamagaki, T., Kimura, Y., Yamazaki, T. “Amidation/Non-amidation Top-down Analysis of Endogenous Neuropeptide Y in Brain Tissue by Nano Flow Liquid Chromatography Orbitrap Fourier Transform Mass Spectrometry.” J. Mass Spectrom. 56, e4716 (2021). [Publisher] (open access)

Watanabe, T., Yamagaki, T., Azuma, T., Horikawa, M. “Distinguishing Between Isomeric Neoxanthin and Violaxanthin Esters in Yellow Flower Petals Using Liquid Chromatography/Photodiode Array Atmospheric Pressure Chemical Ionization Mass Spectrometry and Tandem Mass Spectrometry.” Rapid Commun. Mass Spectrom. 35, e9142 (2021). [Publisher] (open access)

Kabe, Y., Koike, I., Yamamoto, T., Hirai, M., Kanai, A., Furuhata, R., Tsugawa, H,. Harada, E., Sugase, K., Hanadate, K., Yoshikawa, N., Hayashi, H., Noda, M., Uchiyama, S., Yamazaki, H., Tanaka, H., Kobayashi, T., Handa, H., Suematsu, M. “Glycyrrhizin Derivatives Suppress Cancer Chemoresistance by Inhibiting Progesterone Receptor Membrane Component 1.” Cancers 13, 3265 (2021). [Publisher] (open access)

Mizuno, T., Sugahara, K., Tsutsumi, C., Iino, M., Noda, N., Nakayama, M., Iwashina, T. “Anthocyanin and Flavonoids from the Greenish Blue Perianth of Puya alpestris (Bromeliaceae) and its Coloration Mechanism.” Phytochemistry 181, 112581 (2021). [Publisher]

Iwashina, T., Rahayu, S., Sugahara, K., Mizuno, T.; Tsutsumi, C.; Widyatmoko,D. “Acylated pelargonidin and cyanidin 3-sambubiosides from the flowers of Aeschynanthus species and cultivars.” Phytochemistry 192, 11295 (2021). [Publisher]

Sasaki S., Kitamura J., Endo H., Shiraishi A., Ikebukuro K., Mizutani T., Tera M. (2021) Identification of G-quadruplex sequences in severe acute respiratory syndrome coronavirus 2. Translat. Regulat. Sci. 3(3): 89-92. Doi: 10.33611/trs.2021-019 open access.

Takahashi T., Shiraishi A., Murata J., Matsubara S., Nakaoka S., Kirimoto S., Osawa M. (2021) Muscarinic receptor M3 contributes to intestinal stem cell maintenance via EphB/ephrin-B signaling. Life Sci. Alliance 4(9):e202000962. Doi: 10.26508/lsa.202000962 [PubMed] open access.

Matsubara S., Osugi T., Shiraishi A., Wada A., Satake H. (2021) Comparative analysis of transcriptomic profiles among ascidians, zebrafish, and mice: Insights from tissue-specific gene expression PLoS One. 16(9):e0254308. doi: 10.1371/journal.pone.0254308. [PubMed] open access.

Osugi T., Miyasaka N., Shiraishi A., Matsubara S., Satake H. (2021) “Cionin, a vertebrate cholecystokinin/gastrin homolog, induces ovulation in the ascidian Ciona intestinalis type A.” Sci Rep. 11(1):10911. doi: 10.1038/s41598-021-90295-3. [PubMed]. open access.

Daubnerová I., Roller L., Satake H., Zhang C., Kim YJ., Žitňan D. (2021) “Identification and
function of ETH receptor networks in the silkworm Bombyx mori.” Sci Rep. 11(1), 11693. doi:10.1038/s41598-021-91022-8. [PubMed] open access.

Kawada T., Shiraishi A., Matsubara S., Hozumi A., Horie T, Sasakura Y, Satake H. (2021) Vasopressin Promoter Transgenic and Vasopressin Gene-Edited Ascidian, Ciona intestinalis Type A (Ciona robusta): Innervation, Gene Expression Profiles, and Phenotypes. Front Endocrinol (Lausanne). 12, 668564. doi: 10.3389/fendo.2021.668564. eCollection 2021. [PubMed] open access.

Fodor I., Svigruha R., Bozsó Z., Tóth GK.,Osugi T., Yamamoto T., Satake H, Pirger Z. (2021) Functional characterization and related evolutionary implications of invertebrate gonadotropin-releasing hormone/corazonin in a well-established model species. Sci Rep. 11(1), 10028.doi: 10.1038/s41598-021-89614-5. [PubMed]. open access.

Otsuka K., Matsubara S., Shiraishi A., Takei N, Satoh Y, Terao M, Takada S, Kotani T, Satake H., Kimura AP. (2021) A Testis-Specific Long Noncoding RNA, Start, Is a Regulator of Steroidogenesis in Mouse Leydig Cells. Front Endocrinol (Lausanne). 12, 665874. doi: 10.3389/fendo.2021.665874. https://pubmed.ncbi.nlm.nih.gov/33897623/ open access.

Suzuki M., Urabe A., Sasaki S., Tsugawa R., Nishio S., Mukaiyama H., Murata Y., Masuda H., Aung M.S., Mera A., Takeuchi M., Fukushima K., Kanaki M., Kobayashi K., Chiba Y., Shrestha B.B., Nakanishi H., Watanabe T., Nakayama A., Fujino H., Kobayashi T., Tanino K., Nishizawa N.K., Namba K. (2021) “Development of a mugineic acid family phytosiderophore analog as an iron fertilizer.” Nat Commun. 12(1):1558. doi: 10.1038/s41467-021-21837-6. [PubMed]. open access.

Bandara TAMK., Otsuka K., Matsubara S., Shiraishi A., Satake H., Kimura AP. (2021) “A dual enhancer-silencer element, DES-K16, in mouse spermatocyte-derived GC-2spd(ts) cells” Biochem Biophys Res Commun. 534, 1007-1012. doi: 10.1016/j.bbrc.2020.10.049. [PubMed].

Murata Y., Yoshida M., Sakamoto N., Morimoto S., Watanabe T., Namba K. (2021) “Iron uptake mediated by the plant-derived chelator nicotianamine in the small intestine.” J. Biol. Chem. 296, 100195.doi:10.1074/jbc.RA120.015861. [PubMed]. Editor’s Pick. open access.

Mita M, Osugi T., Matsubara S., Kawada T., Satake H., Katayama H. (2021) “A relaxin-like gonad-stimulating peptide identified from the starfish Astropecten scoparius.” Mol. Reprod. Dev. 88, 34-42. doi: 10.1002/mrd.23444. [PubMed] open access.

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