Review & Book 2024

Osawa T., Fujikawa K., Shimamoto K. “Structures, functions, and syntheses of glycero-glycophospholipids.” Front. Chem. 12, 1353688 (2024). [DOI] (open access)

Nomura K., Mori S., Shimamoto K. “Roles of a Glycolipid MPIase in Sec-Independent Membrane Protein Insertion.” Membranes 14, 48 (2024). [DOI] (open access)

Koyama T. “Regulatory mechanisms of transcription factors in plant morphology and function 2.0.” Int. J. Mol. Sci. 25, 2010 (2024). [DOI] (open access)

Takase Y., Takahashi T. “Method for two-dimensional epithelial monolayer formation from mouse three-dimensional small intestinal organoids.” Methods Mol. Biol. 2749, 73–84 (2024). [DOI]

Satake H., Sasakura Y. “The neuroendocrine system of Ciona intestinalis Type A, a deuterostome invertebrate and the closest relative of vertebrates.” Mol Cell Endocrinol. 582, 112122 (2024). [DOI] (open access)

Review & Book 2023

高瀬悠太 「美しい血管パターンが生まれるしくみ: トリ胚から迫る血管ネットワーク形成機構」 遺伝: 生物の科学 77 (4), 275–281 (2023). [Info]

Ono E., Murata J. “Exploring the Evolvability of Plant Specialized Metabolism: Uniqueness Out of Uniformity and Uniqueness Behind Uniformity.” Plant Cell Physiol. 64, 1449–1465 (2023). [DOI] (open access)

高橋俊雄 「腸幹細胞の幹細胞性を支えるアセチルコリンシグナリング」 Medical Science Digest 49(5), 42–45 (2023). [Publisher]

Koyama T. “Regulatory mechanisms of transcription factors in plant morphology and function.” Int. J. Mol. Sci. 24, 7039 (2023). [DOI] (open access)

Satake H. “Kobayashi Award 2021: Neuropeptides, receptors, and follicle development in the ascidian, Ciona intestinalis Type A: New clues to the evolution of chordate neuropeptidergic systems from biological niches.” Gen Comp Endocrinol. 337, 114262 (2023). [DOI] (open access)

Becker A., Yamada Y., Sato F. “California poppy (Eschscholzia californica), the Papaveraceae golden girl model organism for evodevo and specialized metabolism.” Front. Plant Sci. 14, 1084358 (2023). [DOI] (open access)

Review & Book 2022

Fujikawa K., Mori S., Nishiyama K., Shimamoto K. CHAPTER FIVE “A bacterial glycolipid essential for membrane protein integration.” Adv. Carbohydr. Chem. Biochem. 81, 95–129 (2022). [DOI]

Koyama T., Murata J., Horikawa M., Satake H. “Production of beneficial lignans in heterologous host plants. Front. Plant Sci. 13, 1026664 (2022). [DOI] (open access)

佐竹炎 (2022) 「すき間で見つけた石で立派な家を作ることを目指す：小林賞受賞記」比較内分泌学 48(175), e0023

Nishikawa H., Sawasato K., Mori S., Fujikawa K., Nomura K., Shimamoto K., Nishiyama K. “Interaction between glycolipid MPIase and proteinaceous factors during protein integration into the cytoplasmic membrane of E. coli.” Front. Mol. Biosci. 2022, 9, 986602. [DOI] (open access)

Kawada T., Osugi T., Matsubara S., Sakai T., Shiraishi A., Yamamoto T., Satake H. (2022) ”Omics Studies for the Identification of Ascidian Peptides, Cognate Receptors, and Their Relevant Roles in Ovarian Follicular Development.” Front Endocrinol (Lausanne). 13, 858885. [PubMed]

Murata Y., Murata J., Namba K. (2022) ”Unraveling the new biological roles and possibleapplications of phytosiderophores in plants and mammals.” Metallomics Research 2(2).

Review & Book 2021

小埜栄一郎、 村田純、堀川学 「ゴマリグナン酵素進化から学ぶ特化代謝観」 ファルマシア, 57 (8), 715-720 (2021). [Publisher]

山垣亮、木村優佳、山崎尭嗣 「 LC-MS による高感度ペプチド定量分析の問題点と解決法：極微量ペプチド標品の吸着と検量線作成」 J. Mass Spectrom. Soc. Jpn., 69 (2), 23-29 (2021). [Publisher]

Takahashi T., Fujishima K., Kengaku M. (2021) Modeling intestinal stem cell function with organoids. Int. J. Mol. Sci. 22, 10912. [PubMed]

佐竹炎(2021) 「ホヤから見つかったペプチドと受容体からわかったこと」比較生理生化学 38(3), 115-123.

川田剛士(2021) 「バソプレシン遺伝子改変ホヤの解析」比較内分泌学 47, e0003.

Satake H., Osugi T., Shiraishi A. (2021) Impact of Machine Learning-Associated Research Strategies on the Identification of Peptide-Receptor Interactions in the Post-Omics Era. Neuroendocrinology. doi: 10.1159/000518572. Epub ahead of print. [PubMed]

Takahashi T. (2021) Multiple roles for cholinergic signaling from the perspective of stem cell function. Int J Mol Sci. 22, 666. [PubMed]

高橋俊雄 (2021) 「非神経細胞型アセチルコリン受容体を介した腸幹細胞の維持機構の解明」BIO Clinica 36(5), 94-97. BIOLOGY TOPICS

Review & Book 2020

山垣亮、山崎尭嗣、木村優佳「液体クロマトグラフィー質量分析におけるキャリーオーバー問題と解決法」 J. Mass Spectrom. Soc. Jpn., 68 (6), 99-105 (2020). [Publisher]

沢里克宏藤川紘樹島本啓子西山賢一「大腸菌におけるタンパク質膜輸送に関与する糖脂質 MPIase の発現制御機構酵素様機能をもつ糖脂質 MPIase」 化学と生物, 58 (4), 223-230 (2020). [Publisher]

菅原孝太山垣亮緒方是嗣山本卓志「質量分析イメージングを用いたビオラ花弁におけるフラボノイド類の可視化」株式会社島津製作所 Application Note 59, 1-8 (2020).

Sakai T, Yamamoto T, Matsubara S, Kawada T, Satake H. (2020) “Invertebrate Gonadotropin-Releasing Hormone Receptor Signaling and Its Relevant Biological Actions” Int J Mol Sci. 21, 8544. doi: 10.3390/ijms21228544. [PubMed]

Takahashi T, Shiraishi A. (2020) Stem cell signaling pathways in the small intestine. Int J Mol Sci. 21(6), 2032. [PubMed]

Takahashi T. Roles of nAChR and Wnt signaling in intestinal stem cell function and inflammation. Int Immunopharmacol. 81, 106260. [PubMed]

Takahashi T. (2020) Cnidarian peptide signaling molecules. In: Advances Invertebrate (Neuro) Endocrinology, (Eds. Saleuddin S., Lange A.B., Orchard I.), Apple Academic Press, USA, Chapter1, pp. 1-24.

Takahashi T.(2020) Comparative Aspects of Structure and Function of Cnidarian Neuropeptides. Front. Endocrinol. 11, 339. [PubMed]

高橋俊雄(2020)「非神経細胞型アセチルコリン受容体を介した腸幹細胞の分化・増殖制御機構の解明」Precision Medicine 3(6), 88 –91.「研究者の最新動向」

三田雅敏、大杉知宏、高橋俊雄、渡辺健宏、佐竹炎(2020)「ヒトデの配偶子放出のメカニズム：ヒトデの放卵・放精はアセチルコリンによる Ca2+-influx により誘起される」比較内分泌学 146, 79-81.

Review & Book 2019

Fujikawa, K.; Nishiyama, K. I.;Shimamoto, K.“Enzyme-like glycolipids MPIase involved in membrane protein integration of E. coli” Trends. Glycosci. Glyc., 31, E151-E158 [Publisher]; J149-J155 [Publisher] (2019).

Fujikawa, K.; Nomura, K.; Nishiyama, K. I.; Shimamoto, K. “Novel glycolipid involved in membrane protein integration: Structure and mode of action” J. Synth. Org. Chem. Jpn. 77, 1096-1105 (2019). [Publisher]

野村薫「GPI アンカー型タンパク質における脂質アンカーの役割解明」生物物理, 59(6), 295-299 (2019). [Publisher]

Nässel DR, Zandawala M, Kawada T, Satake H. (2019) “Tachykinins: Neuropeptides That Are Ancient, Diverse, Widespread and Functionally Pleiotropic.” Front Neurosci. 13, 1262. [PubMed]

Satake H, Larhammar D, Elphick MR. (2019) Editorial: “Endocrine and Neuroendocrine Systems of Invertebrate Deuterostomes.” Front Endocrinol (Lausanne). 10, 755. [PubMed]

佐竹炎、白石慧 (2019) 「機械学習を活用したペプチド‐受容体ペアの予測と実証」バイオサイエンスとバイオインダストリー 55, 478－480.

佐竹炎、白石慧 (2019) 「そのマッチング、人工知能（AI）の力でお助けします –機械学習を駆使した新規ペプチド-受容体の高精度予測と実証」比較内分泌学 45, 108－111.

佐竹炎、白石慧 (2019) 「見えないものを見抜く–機械学習を駆使した新規ペプチド受容体の高精度予測と実証」ファルマシア 55, 924－928.

Satake H, Matsubara S, Shiraishi A, Yamamoto T, Osugi T, Sakai T, Kawada T. (2019) “Neuropeptides, Peptide Hormones, and Their Receptors of a Tunicate, Ciona intestinalis.” Results Probl Cell Differ. 68, 107-125. [PubMed]

Satake H, Matsubara S, Shiraishi A, Yamamoto T, Osugi T, Sakai T, Kawada T. (2019) “Peptide receptors and immune-related proteins expressed in the digestive system of a urochordate, Ciona intestinalis.” Cell Tissue Res. 377(3), 293-308. [PubMed]

高橋俊雄 (2019) 「非神経性アセチルコリンによる腸幹細胞の分化・増殖、維持機構の解明」 Medical Science Digest 45(9), 41-43「Cutting Edge」

Takahashi T.(2019) “New trends and perspectives in the function of non-neuronal acetylcholine in crypt-villus organoids in mice.” Methods Mol. Biol. 1576, 145-155. [PubMed]

Takahashi T. (2019) “Organoids for Drug Discovery and Personalized Medicine.” Annu. Rev. Pharmacol. Toxicol. 59, 447-462. [PubMed]

Takahashi T. (2019) “Cnidarian peptide signaling molecules. Advances Invertebrate (Neuro)Endocrinology (Book Title), Saber saleuddin, Angela B. Lange, Ian Orchard (Editors), APPLE ACADEMIC PRESS.” In Press.

川田剛士、佐竹炎 (2019) 「オキシトシン/バソプレシンファミリーの起源と進化」脳神経内科 90, 261-269.

梅澤俊明、山村正臣、小埜栄一郎、白石慧、サフェンドリ・コマーラ・ラガムスタリ (2019) 「リグナン OMT に関する最新研究動向」木材学会誌 65(1), 1-12.

堀川学、小山知嗣、寺正行 (2019) 「植物におけるセサミン結合タンパク質の同定と機能探索」バイオサイエンスとインダストリー（印刷中）

Review & Book 2018

山垣亮「UV-MALDI-MS によるフラボノイド配糖体構造異性体の識別とレーザー励起による水素ラジカル脱離」J. Mass Spectrom. Soc. Jpn., 66(5), 197-203 (2018). [Publisher]

堀川学山本将之小埜栄一郎村田純「ひらけごま！見えてきたゴマリグナンの生合成機構」化学と生物, 56 (11), 738-746 (2018). [Publisher]

藤川紘樹「シャペロン様活性を有する糖鎖類縁体」Trends. Glycosci. Glyc., 30, E241-E243 [Publisher]; J201-J202 [ Publisher](2018).

Namba K, Murata Y. (2018) “Organic Chemistry Research on the Mechanistic Elucidation of Iron Acquisition in Barley.” Biol Pharm Bull. 41(10):1502-1507. [J-Stage]]

村田佳子 (2018) 第 20 章ムギネ酸 p133-140、化学のとびら 64 天然物の化学 II 自然からの贈り物上村大輔編東京化学同人

Koyama T. (2018) “A hidden link between leaf development and senescence”. Plant Sci. 276, 105-110. [PubMed]

小山知嗣 (2018)「葉の形を決めるマイクロ RNA ネットワーク」化学と生物 56, 774-776.[J-Stage]

山本将之、堀川学、村田純、小埜栄一郎 (2018) 「代謝酵素が広げるゴマリグナンの多様性」 Sesame Newsletter (日本ゴマ科学会誌)

Review & Book 2017

藤川紘樹「グリコシル化反応における水素結合」Trends. Glycosci. Glyc., 29, E99-E100 [Publisher]; J75-J76 [Publisher] (2017).

Sakai T, Shiraishi A, Kawada T, Matsubara S, Aoyama M, Satake H. (2017) “Invertebrate Gonadotropin-Releasing Hormone-Related Peptides and Their Receptors: An Update.” Front Endocrinol (Lausanne)8 , 217. [PubMed]

高橋俊雄 (2017) 「質量分析でアセチルコリンを”可視化する”技」比較内分泌学 43(162) 141-142.

Satake H, Shiraishi A, Koyama T, Matsumoto E, Morimoto K, Bahabadi, SE, Ono E, Murata J. (2017) “Lignan biosynthesis for food bioengineering. Handbook of Food Bioengineering”, Grumezescu AM and Holban AM, (eds.) p351-p379, Elsevier Inc, Netherland.

Review & Book 2016

Shimamoto, K. “Elucidation of excitatory neurotransmission and membrane protein integration mechanisms.” Bull. Chem. Soc. Jpn., 89, 282-295 (2016). [Publisher]

山垣亮「LC/MSのためのエレクトロスプレーイオン化法：基礎」J.Mass Spectrom. Soc. Jpn. 63, 11-16 (2016). [Publisher]

島本啓子「脂質と膜タンパク」天然物の化学－魅力と展望－上村大輔編（東京化学同人）139-146 (2016) [Publisher]

Matsubara, S., Kawada, T., Sakai, T., Aoyama, M., Osugi, T., Shiraishi, A., Satake, H. (2016) “The significance of Ciona intestinalis Äi0as a stem organism in integrative studies of functional evolution of the chordate endocrine, neuroendocrine, and nervous systems.” Gen. Comp. Endocrinol. 227, 101-108. [PubMed]

Osugi, T., Son, Y.L., Ubuka, T., Satake, H., Tsutsui, K. (2016) “RFamide peptides in agnathans and basal chordates.” Gen. Comp. Endocrinol. 227, 94-100. [PubMed]

Satake, H., Koyama, T., Matsumoto, E., Morimoto, K., Ono, E., Murata, J.(2016). “Metabolic Engineering of Lignan Biosynthesis Pathways for the Production of Transgenic Plant-Based Foods.” In: Transgenesis and Secondary Metabolism (Sumita Jha ed.). Springer International Publishing, Gewerbestrasse, Switzerland, pp. 1-26. [Publisher]

荒木良一、村田佳子、村田純 (2016)「アミノ酸類縁体、ムギネ酸類の植物生長促進メカニズムの解明、京都大学RIセンターニュース 60, 8-10.

高橋俊雄 (2016) 「多段階質量分析イメージングによる腸上皮組織中のアセチルコリン分布とその役割」比較内分泌学 42(158) 49-50.

高橋俊雄 (2016) 「CompBiol 2015 合同シンポジウム」「”ポストオミクス時代における画像解析の最前線”顛末記」比較生理生化学 33(1) 22-24.

Review & Book 2015

菅原孝太郎「NMRを使って天然物の構造を調べる」現代化学, ６月号, 36-37 (2015). [Publisher]

Satake, H., Koyama, T., Bahabadi, S.E., Matsumoto, E., Ono, E., Murata, J. (2015) “Essences in metabolic engineering of lignan biosynthesis.” Metabolites. 5, 270-290. [PubMed]

Araki R, Namba K, Murata Y, Murata J. (2015) Phytosiderophores revisited: 2’-deoxymugineic acid-mediated iron uptake triggers nitrogen assimilation in rice (Oryza sativa L.) seedlings. Plant Signal. Behav. 10, e1031940. [PubMed]

Takahashi, T. (2015) “Non-neuronal functions of acetylcholine via muscarinic receptor subtypes: cellular proliferation and differentiation in mammals.” Neurotransmitter 2, e499.[Smart Science Technology]

Takahashi, T., Takeda, N. (2015) “Insight into the molecular and functional diversity of cnidarian neuropeptides.” Int. J. Mol. Sci. 16, 2610-2625. [PubMed]

森下文浩、高橋俊雄 (2015) 「研究者が教える動物実験」生理活性ペプチドを“見つける”技」日本比較生理生化学会編集 2, 187-190.

高木基成、白石慧、小埜栄一郎 (2015) 「ホップゲノムから栽培化の歴史を紐解く」バイオサイエンスとインダストリー 73(4), 297-299.

小山知嗣 (2015) 「葉の凹凸形態形成の制御機構」BSJ review 6, 112-125. [Publisher]

Martinis D, Koyama T, Chang C. (2015) “Ethylene is all around”. Front. Plant Sci. 6, 76 [PubMed]

Review & Book 2014

Nomura,K., Kusumoto,S. “CHAPTER 9, Lipopolysaccharide induces raft domain expansion in a cholesterol-containing membrane” in Advances in Biological Solid-State NMR : Proteins and membrane-active peptides (Separovic F. and Naito A. eds.), Royal Society of Chemistry, Rondon, 162-179 (2014). [Publisher]

Nishiyama, K., Shimamoto, K. “Glycolipozyme membrane protein integrase (MPIase): recent data. ” BioMolecular Concepts, 5, 429-438.(2014). [Publisher]

島本啓子西山賢一「タンパク質ではない酵素？－タンパク質膜挿入の鍵を握るグライコリポザイム」「実験医学増刊驚愕の代謝システム」実験医学, 32, 115-122 (2014). [Publisher]

Koyama T. (2014) “Roles of ethylene and transcription factors in the regulation of onset of leaf senescence.” Front. Plant Sci. 5, 650. [PubMed]

Review & Book 2013

西山賢一島本啓子「膜タンパク質の鍵は糖脂質にあり－すべての生体膜挿入に必要な因子を求めて－」化学 68, 30-34 (2013) [Publisher]

Satake, H., Matsubara, S., Aoyama, M., Kawada, T. Sakai, T.(2013) “GPCR heterodimerization in the reproductive system: functional regulation and implication for biodiversity.” Front. Endocrinol. 4, 100. [PubMed]

Satake, H., Ono, E., Murata, J. (2013) “Recent advances in metabolic engineering of lignan biosynthesis pathways for the production of transgenic plant-based foods and supplements” J. Agric. Food Chem. 61, 11721-11729. [PubMed]

Satake, H., Aoyama, M., Sekiguchi, T., Kawada, T. (2013) “Insight into molecular and functional diversity of tachykinins and their receptors” Prot. Pept. Lett. 20, 615-627. [PubMed]

Kawada, T., Aoyama, M., Sakai, T., Satake, H. (2013) “Structure, function, and evolutionary aspects of invertebrate GnRHs and their receptors.” In: Gonadotropin-Releasing Hormone (GnRH): Production, Structure and Functions. Nova Science Publishers Inc. pp. 1-16. [Publisher]

Takahashi, T. (2013) “Neuropeptides and epitheliopeptides: Structure and functional diversity in an ancestral metazoan Hydra.” Prot. Pept. Lett. 20, 671-680. [PubMed]

Review & Book 2012

荒木良一 (2012)「オオムギのムギネ酸類金属錯体輸送体の解明」バイオサイエンスとインダストリー 70, 280-281.

Satake, H., Sekiguchi, T., Sakai, T., Aoyama, M. Kawada, T. (2012) “Endocrinology and neuroendocrinology of protochordates: evolutionary views and potentials as new model organisms.” Recent Res. Devel. Endocrinol. 5, 1-19.

川田剛士 (2012) 「オキシトシン / バソプレシンファミリーペプチドの起源を探る」比較内分泌学 38, 116－121.

Satake, H., Sekiguchi, T. (2012) “Toll-like receptors of deuterostome invertebrates.” Front. Immunol. 3, 34. [PubMed]

Takahashi, T., Horikawa, M. (2012) Evolutionary aspects of molecular forms and biological functions of acetylcholinesterase in Handbook of Cholinesterase: Production, Uses and Health Effects. (Cecelia J.W. and Janice E.T. eds.), Nova Science Publications, Inc. Hauppauge, NY, pp147-163. [Publisher]

Review & Book 2011

Satake, H., Kawada, T., Aoyama, M., Sekiguchi, T., Sakai, T. (2011) “Ascidians: new model orgnanisms for reproductive endocrinology” In: Update on Mechanisms of Hormone Action – Focus on Metabolism, Growth and Reproductions. (Gianluca Aimaretti, Paolo Marzullo, and Flavia Prodam eds), IN-TECH, Vienna, Austria, pp. 313-336. [Publisher]

佐々木尚子、関口俊男、楠本正一、佐竹炎 (2011) 「脊椎動物祖先型生物ホヤはハイブリッド型の Toll 様受容体を持つ」エンドトキシン・自然免疫研究 14, 75-78.

小埜栄一郎、佐竹炎 (2011)「ゴマリグナン生合成経路と代謝工学」バイオインダストリー 28, 27-33.

佐竹炎、畑直樹、岡澤敦司「リグナンの代謝工学的生産を目指した基盤研究」(2011) バイオサイエンスとインダストリー 69, 289-293.

Takahashi, T., Hatta, M. (2011) “The importance of GLWamide neuropeptides in cnidarians development and physiology.” J. Amino Acids 2011, ID 424501. [PubMed]

Review & Book 2010

佐竹炎 (2010)「ホヤの神経ペプチド・ペプチドホルモンの研究でわかったこととその意義」比較内分泌学 36, 242-264.

Nonaka, M., Satake, H. (2010) “Urochordate immunity.” Adv. Exp. Med. Biol. 708, 302-310. [PubMed]

Satake, H., Sasaki, N. (2010) “Comparative view on Toll-like receptors of lower animals.” Zool. Sci. 27 154-161. [PubMed]

Kawada, T., Sekiguchi, T., Sakai, T., Aoyama, M., Satake, H. (2010) “Neuropeptides, hormone peptides, and their receptors in Ciona intestinalis: an update.” Zool. Sci. 27 134-153. [PubMed]

村田佳子 (2010)「ムギネ酸類によるイネ科植物の鉄取り込み機構」化学と生物 48, 528-534. [J-Stage]

Namba, K., Murata, Y. (2010) “Toward mechanistic elucidation of iron acquisition in barley: efficient synthesis of mugineic acids and their transport activities.” The Chemical Record, 10, 140-150. [PubMed]

高橋俊雄 (2010) 「ペプチド分子：その構造と機能の多様性」日本比較生理生化学会「動物の生きるしくみ事典」（http://wiki.jscpb.org/動物の生きるしくみ事典）

Takahashi, T., Fujisawa, T., (2010) “Peptidomic approaches to the identification and characterization of functional peptides in Hydra.” Methods Mol. Biol. 615, 275-292. [PubMed]

研究成果